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Off-label, it may be used for conditions such as Barretts esophagus and in combination with antibiotics to treat Helicobacter pylori infections

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A recent study demonstrated the successful delivery of IRAK4 inhibitors across the BBB in mice using dual peptide-functionalized polymeric NPs, highlighting their translational potential [192]

For nausea Nausea is the most commonly reported side effect, particularly during dose increases 3

As one of the main components, crocin improved depressive symptoms and reduced the expression of inflammatory cytokines (e.g., IL-1, IL-18, and TNF-) in the hippocampus of LPS-depressed mice (96)